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Seiichiro Fujisawa Selected Research

Neoplasms (Cancer)

3/2015Anti-inflammatory activity of the artificial antioxidants 2-tert-butyl-4-methoxyphenol (BHA), 2,6-di-tert-butyl-4-methylphenol (BHT) and 2,4,6-tri-tert-butylphenol (TBP), and their various combinations.
7/2013Inhibitory effects of tocopherols on expression of the cyclooxygenase-2 gene in RAW264.7 cells stimulated by lipopolysaccharide, tumor necrosis factor-α or Porphyromonas gingivalis fimbriae.
2/2009Mechanisms of cytotoxicity of 2- or 2,6-di-tert-butylphenols and 2-methoxyphenols in terms of inhibition rate constant and a theoretical parameter.
5/2008Comparative study of the alkyl and peroxy radical-scavenging activity of 2-t-butyl-4-methoxyphenol (BHA) and its dimer, and their theoretical parameters.
1/2007Comparative cytotoxicity and ROS generation by curcumin and tetrahydrocurcumin following visible-light irradiation or treatment with horseradish peroxidase.
10/2006Induction of early apoptosis and ROS-generation activity in human gingival fibroblasts (HGF) and human submandibular gland carcinoma (HSG) cells treated with curcumin.
1/2006Anti- and pro-oxidant effects of oxidized quercetin, curcumin or curcumin-related compounds with thiols or ascorbate as measured by the induction period method.
11/2005Induction of cytotoxicity and apoptosis and inhibition of cyclooxygenase-2 gene expression, by curcumin and its analog, alpha-diisoeugenol.
1/2005Cytotoxic activity of styrylchromones against human tumor cell lines.
1/2005Dimerization, ROS formation, and biological activity of o-methoxyphenols.
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Seiichiro Fujisawa Research Topics

Disease

13Neoplasms (Cancer)
03/2015 - 01/2002
7Periodontal Diseases (Periodontal Disease)
01/2020 - 02/2005
4Carcinogenesis
03/2019 - 11/2004
4Carcinoma (Carcinomatosis)
10/2006 - 08/2002
3Inflammation (Inflammations)
11/2018 - 02/2005
3Leukemia
11/2005 - 11/2003
2Necrosis
03/2015 - 11/2003
1Bacterial Infections (Bacterial Infection)
01/2020
1Alveolar Bone Loss
11/2018
1Persistent Infection
11/2015
1Chronic Disease (Chronic Diseases)
07/2013
1Periodontitis
01/2012
1Chronic Periodontitis
07/2006
1Leukoplakia
07/2006
1Reperfusion Injury
03/2006
1Adenocarcinoma
03/2004
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
11/2003

Drug/Important Bio-Agent (IBA)

7Butylated Hydroxyanisole (BHA)IBA
03/2015 - 08/2002
5EugenolIBA
02/2009 - 08/2002
4CurcuminIBA
01/2007 - 03/2004
3AntioxidantsIBA
03/2015 - 05/2006
3Butylated Hydroxytoluene (BHT)IBA
03/2015 - 11/2003
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2007 - 01/2005
2Biological ProductsIBA
03/2019 - 03/2006
2Cyclooxygenase 2 (Cyclooxygenase-2)IBA
03/2015 - 01/2012
2Free RadicalsIBA
07/2013 - 03/2006
2Fibronectins (Fibronectin)IBA
01/2012 - 02/2005
2NF-kappa B (NF-kB)IBA
01/2012 - 02/2005
22-tert-butyl-4-hydroxyanisoleIBA
07/2006 - 05/2006
2diisoeugenolIBA
11/2005 - 02/2005
2Matrix Metalloproteinases (MMPs)IBA
09/2005 - 09/2004
2Oxygen (Dioxygen)IBA
01/2005 - 03/2004
1Ointments (Pastes)IBA
01/2020
1Tetracycline (Achromycin)FDA LinkGeneric
01/2020
1MethacrylatesIBA
11/2018
1hydroxyethyl methacrylate (HEMA)IBA
11/2018
1ethyl acrylateIBA
11/2018
1AcrylatesIBA
11/2018
1cinnamic acidIBA
11/2018
1methyl cinnamateIBA
11/2018
1CinnamatesIBA
11/2018
1triethylene glycol dimethacrylate (TEGMA)IBA
11/2018
1acrylic acid (acrylate)IBA
11/2018
1cinnamaldehyde (cinnamic aldehyde)FDA Link
11/2018
1FlavonoidsIBA
11/2015
1QuercetinIBA
11/2015
1ResveratrolIBA
05/2015
1PhenolsIBA
03/2015
12,4,6-tri-tert-butylphenolIBA
03/2015
1tributyl phosphate (TBP)IBA
03/2015
1Tocopherols (Tocopherol)IBA
07/2013
1LipopolysaccharidesIBA
01/2012
1MelatoninIBA
01/2012
1CytokinesIBA
01/2012
1Horseradish PeroxidaseIBA
01/2007
1tetrahydrocurcuminIBA
01/2007
1Glutathione (Reduced Glutathione)IBA
01/2007
1Transcription Factor AP-1 (Transcription Factor AP 1)IBA
07/2006
1CarbonIBA
03/2006
1creosolIBA
09/2005
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
02/2005
1dehydrodiisoeugenolIBA
02/2005
1TamoxifenFDA LinkGeneric
11/2004
1Diethylstilbestrol (Stilbestrol)FDA Link
11/2004
1Estrogens (Estrogen)FDA Link
11/2004
1EstroneFDA Link
11/2004
1Toremifene (Fareston)FDA Link
11/2004
1Estrogen Receptor Modulators (Antiestrogen)IBA
11/2004
1quinone methideIBA
09/2004
1isoeugenolIBA
03/2004
1Caspase 3 (Caspase-3)IBA
11/2003
12-tert-butyl-4-methylphenolIBA
11/2003
1ferulic acid (sodium ferulate)IBA
09/2002
1AlkaloidsIBA
01/2002
1cepharanthineIBA
01/2002

Therapy/Procedure

1Photochemotherapy (Photodynamic Therapy)
01/2020
1Chemoprevention
01/2006
1Drug Therapy (Chemotherapy)
01/2005